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Lamictal (Lamotrigine) monotherapy for typical absence seizures in children.

L Matthew Frank et Al.

Epilepsia 40(7); 973-979, 1999

This a complicated study which is very well designed using placebo controlled, double-blind testing of LMT for control of absence seizures. Classical treatment for absences includes either Valproic Acid or Ethosuximide.

This study shows without ambiguity that lamictal is as effective and as safe as VPA or ESM in the treatment of absences. It appears that LMT is a safe alternate treatment.